FIGURE

Fig. 3

ID

ZDB-FIG-070502-30

Publication

Hagos et al., 2007 - Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish

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Fig. 3

Treatment at MBT blocks the response to receptors activated during the cleavage stages. Embryos injected at the 1–4 cell stage with 10pg β-galactosidase (A-D), TARAM-D (E-H), or sqt (I-L) mRNA, and treated at 2.75 h with DMSO (A, E, I, C, G, K) or SB-431542 (B, F, J, D, H, L). (E, G) TARAM-D induces ectopic body axes and gsc expression. (F, H) The effects of TARAM-D are suppressed by treatment with SB-431542. (I, K) sqt overexpression arrests epiboly and induces ubiquitous expression of gsc. (J, L) The response to ubiquitous Sqt is blocked by treatment with SB-431542. Images of live embryos at 30 h, anterior to the left (A, B, E, F, I, J). Animal pole views of fixed embryos at 5 h, dorsal to the right (C, D, G, H, K, L).

Expression Data

Gene:	gsc
Fish:	WIK
Condition:	chemical treatment: pharmaceutical
Anatomical Term:	margin
Stage:	30%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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