Fig. 5

The phenotypes of little richard (lit) and golas (gos) mutants. At 3 dpf the ear of lit^m433 (B,E) is markedly smaller than its wild-type counterpart (A,D). In the wild-type larva the semicircular canals are well developed at this stage (D). In contrast, formation of semicircular canals in lit^m433 mutants is not initiated (E). At 3 dpf the ear of gos^m241 is smaller than its wild-type counterpart and has abnormal shape (C, compare with A). The gos^m618 mutation produces a much more pronounced reduction of ear size (F, compare with the wild type in D). (G) Wild-type expression of msx-C at 60 hpf (arrows). (H) msx-C is not expressed in lit^m433 at 60 hpf. Arrowheads in A and B indicate positioning of the pectoral fin. In all panels anterior is left and dorsal up.