ZFIN ID: ZDB-FIG-070306-12
Malicki et al., 1996 - Mutations affecting development of the zebrafish ear. Development (Cambridge, England)   123:275-283
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Pec-fin
PHENOTYPE:
Fish:
Observed In:
Stage Range: Pec-fin to Protruding-mouth

Fig. 5 The phenotypes of little richard (lit) and golas (gos) mutants. At 3 dpf the ear of litm433 (B,E) is markedly smaller than its wild-type counterpart (A,D). In the wild-type larva the semicircular canals are well developed at this stage (D). In contrast, formation of semicircular canals in litm433 mutants is not initiated (E). At 3 dpf the ear of gosm241 is smaller than its wild-type counterpart and has abnormal shape (C, compare with A). The gosm618 mutation produces a much more pronounced reduction of ear size (F, compare with the wild type in D). (G) Wild-type expression of msx-C at 60 hpf (arrows). (H) msx-C is not expressed in litm433 at 60 hpf. Arrowheads in A and B indicate positioning of the pectoral fin. In all panels anterior is left and dorsal up.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
msx3 AB standard conditions Pec-fin otic vesicle protrusion ISH
litm433/m433(AB) standard conditions Pec-fin Not Detected otic vesicle protrusion ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
litm433/m433(AB) standard conditions Pec-fin otic vesicle protrusion aplastic, abnormal
Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth semicircular canal aplastic, abnormal
sox10m241/m241(AB) standard conditions Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth otic vesicle shape, abnormal
Protruding-mouth otolith decreased distance otolith, abnormal
Protruding-mouth otolith decreased size, abnormal
sox10m618/m618(AB) standard conditions Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth otolith decreased distance otolith, abnormal
Protruding-mouth otolith decreased size, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.