ZFIN ID: ZDB-FIG-070219-36
Uechi et al., 2006 - Ribosomal protein gene knockdown causes developmental defects in zebrafish. PLoS One   1(1):e37 Full text @ PLoS One
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 2 Specific Morphological Changes in Brain and Body Trunk Examples of morphants displaying characteristic deformations are shown. The targeted genes and the deformed areas of the morphants are indicated. (A, E) Wild type (WT). (B) rps15; enlarged 4th ventricle (white arrow). (C) rps29; enlarged lens (arrowhead) and undulated rhombencephalon (white arrow). (D) rpl28; protruded forehead. (F) rps3a; wider trunk and downward-curving tail. (G) rps29; wavy notochord and extremely bent tail. (H) rpl35a; sharply downward bent tail. Anterior is to the left. Bars: A~D, 100 μm; E~H, 200 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-rpl28 standard conditions Prim-5 head protruding, abnormal
AB + MO1-rps15 standard conditions Prim-5 fourth ventricle increased size, abnormal
AB + MO1-rps29 standard conditions Prim-5 hindbrain undulate, abnormal
Prim-5 lens increased size, abnormal
AB + MO1-rps3a standard conditions Prim-5 post-vent region curved, abnormal
Prim-5 trunk increased width, abnormal
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