FIGURE

Fig. 6

ID

ZDB-FIG-061205-14

Publication

Sato et al., 2006 - Semaphorin3D regulates invasion of cardiac neural crest cells into the primary heart field

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

sema3D morphants have normal precardiomyocytes in LPM before neural crest arrival and diminished number of cardiomyocytes later. Dorsal views cmlc2 expression in control (A, A′) and sema3D-aug morphants (B, B′) at the 16 SS. Panels A′ and B′ are magnified cmlc2 expression pattern. (C) Schematic diagram of width (W) along the proximal–distal axis and height (H) along the anterior–posterior axis of cmlc2 expression (purple). Graphs indicate mean ± one standard deviation of width and height measured (μm) in sema3D morphants (red circles, n = 32) and controls (blue triangles, n = 37). Before the arrival of neural crest cells, the size of the primary heart field in sema3D morphants is similar to or slightly larger than the heart field in controls. *P = 0.624, **P = 0.09, ***P = 0.005.

Expression Data

Gene:	myl7
Fish:	WT WT + MO2-sema3d
Knockdown Reagent:	MO2-sema3d
Anatomical Term:	heart primordium
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 298(1), Sato, M., Tsai, H.J., and Yost, H.J., Semaphorin3D regulates invasion of cardiac neural crest cells into the primary heart field, 12-21, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.