FIGURE

Fig. 3

ID

ZDB-FIG-061204-9

Publication

Chen et al., 1997 - Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Cardiac BMP4 asymmetry is disturbed in laterality mutants. (A,C) Normally, BMP4 transcripts accumulate predominantly on the left side of the heart tube at the 22-somite stage. (B) At the same stage, Nkx2.5 expression in the heart is symmetric. In those mutant embryos in which the heart fails to jog, such as floating head (flh), BMP4 is more evenly distributed in the heart (D). Mutants with a higher incidence of right-jogged heart, such as iguana (igu), have a higher incidence of right-dominant cardiac BMP4 (E). All are dorsal view, anterior to the bottom of the panel. Lines mark the midline. L, embryo left.

Expression Data

Genes:	bmp4 nkx2.5
Fish:	WT dzip1^{ts294e/ts294e} noto^n1/n1 (AB)
Anatomical Term:	heart primordium
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development