FIGURE

Fig. 3

ID

ZDB-FIG-060629-3

Publication

Wendik et al., 2004 - Zebrafish mnx genes in endocrine and exocrine pancreas formation

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Fig. 3

Tissue-specific expression of hb9 in endocrine pancreas. Expression of hb9 in purple at 15 somite (A), 20 hpf (B, C), 24 hpf (D, E), 28 hpf (F), 36 hpf (G, H) and 48 hpf (I, J). Between 15 somite stage (inlay in A shows a dorsal view of the same embryo in a higher magnification) and 24 hpf endodermal hb9 expression changes from an elongated mono-layered domain to a condensed structure underlying the hypochord (hc). (B–E) Bright field (B, D) and fluorescence (C, E) images of double in situ stains for hb9 (NBT/BCIP) and insulin (Fast Red) show expression of insulin in most hb9-expressing cells; asterisks mark examples for double-labeled cells. Further indicated are hb9 expression domains in the spinal cord (sc), rhombomeres 5 and 6 (white arrowheads) and the swim bladder (black arrowheads). Embryos are shown from a lateral (A, F, G, I) or dorsal view (B, C, D, E, H, J) with anterior to the left. Scale bars correspond to 20 μm.

Expression Data

Genes:	ins mnx1
Fish:	WT
Anatomical Terms:	hypochord pancreas primordium posterior pancreatic bud primary islet rhombomere rhombomere 5 rhombomere 6 spinal cord spinal cord neural rod spinal cord neural tube ventral region swim bladder bud tail bud
Stage Range:	14-19 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 268(2), Wendik, B., Maier, E., and Meyer, D., Zebrafish mnx genes in endocrine and exocrine pancreas formation, 372-383, Copyright (2004) with permission from Elsevier. Full text @ Dev. Biol.