FIGURE
Fig. 8
Fig. 8
Hyperactive BMP signaling in lateral mesoderm restricts hemato-vascular development. Shown are representative sibling embryos that were either control (A,C) or transgenic for the lmo2:caBR transgene (B,D). Embryos were fixed at the 12-somite stage and processed by in situ hybridization to detect the expression patterns of the gata1 gene (A,B; marking committed hematopoietic cells) or the scl gene (C,D; marking hemato-vascular progenitors). The patterns (indicated in the caudal lateral mesoderm by arrows) are markedly repressed by expression of the hyper-activated receptor. |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage: | 10-13 somites |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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