Differential effects of loss of fibroblast growth factor (Fgf) signaling and gain of bone morphogenetic protein (Bmp) or ΔNp63 function on hoxb1b and n-cadherin expression. A-D: In situ hybridizations for hoxb1b (posterior neuroectoderm) at midgastrula stage (80% epiboly), lateral views, dorsal to the right. E-H: In situ hybridizations for ncadherin (ncad), late segmentation stage (24 hours postfertilization), lateral views, anterior to the left, dorsal up. Injected mRNAs and SU5402 treatments (SU) are indicated in upper right corner. E: Arrow indicates ncad-positive cells in the spinal cord of the trunk region. G: bmp2b mRNA-injected embryo displays strongest ventralization (V5; onion-like morphology; Kishimoto et al., 1997)
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