CRISPR

CRISPR5-atm

ID
ZDB-CRISPR-250725-6
Name
CRISPR5-atm
Previous Names
None
Target
Sequence
5' - GTCACTTTCACCTGGCCGG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "AGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf4268 atm
Expression
Gene expression in Wild Types + CRISPR5-atm
No data available
Phenotype
Phenotype resulting from CRISPR5-atm
No data available
Phenotype of all Fish created by or utilizing CRISPR5-atm
Phenotype Fish Conditions Figures
interrenal gland neuroblastoma increased amount, abnormal zdf16Tg/zdf16Tg + CRISPR5-atm standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland neuroblastoma increased amount, abnormal atmzf4268/zf4268; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland cell cycle G2/M phase transition increased occurrence, abnormal atmzf4268/+; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 4 with image from Hayes et al., 2025
interrenal gland neuroblastoma neoplastic, metastatic, exacerbated atmzf4268/+; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 2 with image from Hayes et al., 2025
interrenal gland cell cycle G1/S phase transition increased occurrence, abnormal atmzf4268/+; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 4 with image from Hayes et al., 2025
heart neuroblastoma ab7-h2afx labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
liver neuroblastoma ab7-h2afx labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
olfactory pit neuroblastoma ab7-h2afx labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland nucleus Ab1-pcna labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
gill neuroblastoma ab7-h2afx labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland nucleus low brightness, exacerbated atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland nucleus ab7-h2afx labeling increased amount, abnormal atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 1 with image from Hayes et al., 2025
interrenal gland neuroblastoma neoplastic, metastatic, exacerbated atmzf4268/zf4268; tp53fb105/fb105; zdf16Tg/zdf16Tg standard conditions Fig. 2 with image from Hayes et al., 2025
Citations
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