CRISPR

CRISPR3-rlbp1b

ID
ZDB-CRISPR-230803-1
Name
CRISPR3-rlbp1b
Previous Names
None
Target
Sequence
5' - GGAGCTCAGAGGAATAATCA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zh9 rlbp1b
Expression
Gene expression in Wild Types + CRISPR3-rlbp1b
No data available
Phenotype
Phenotype resulting from CRISPR3-rlbp1b
No data available
Phenotype of all Fish created by or utilizing CRISPR3-rlbp1b
Phenotype Fish Conditions Figures
Muller cell ab1-rlbp labeling decreased amount, abnormal rlbp1bzh9/zh9 standard conditions Figure 1 with image from Schlegel et al., 2021
retinoid metabolic process decreased process quality, abnormal rlbp1bzh9/zh9 low light intensity, high light intensity Figure 2 with image from Schlegel et al., 2021
eye rlbp1b expression decreased amount, abnormal rlbp1bzh9/zh9 standard conditions Figure 1 with image from Schlegel et al., 2021
retina rho expression amount, ameliorated rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 6 with image from Schlegel et al., 2021
Muller cell ab1-rlbp labeling decreased amount, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 1 with image from Schlegel et al., 2021
retina ventral region lesioned, ameliorated rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 7 with image from Schlegel et al., 2021
retinal outer nuclear layer decreased thickness, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 7 with image from Schlegel et al., 2021
retinal outer nuclear layer decreased thickness, ameliorated rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 7 with image from Schlegel et al., 2021
retina ventral region lesioned, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 7 with image from Schlegel et al., 2021
retinal pigmented epithelium ab1-rlbp labeling decreased amount, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 1 with image from Schlegel et al., 2021
ON-bipolar cell response to light intensity decreased process quality, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 low light intensity, high light intensity Figure 3 with image,  Figure 4 with image from Schlegel et al., 2021
retinoid metabolic process decreased process quality, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 low light intensity, high light intensity Figure 2 with image from Schlegel et al., 2021
retina lipid droplet formation increased occurrence, abnormal rlbp1azh8/zh8; rlbp1bzh9/zh9 standard conditions Figure 7 with image from Schlegel et al., 2021
Citations
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