CRISPR

CRISPR1-inhbab

ID

ZDB-CRISPR-220815-6

Name

CRISPR1-inhbab

Previous Names

None

Target

inhbab (1)

Sequence

5' - GGGCAGCACACTGTCAGTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
umo28	inhbab

Expression

Gene expression in Wild Types + CRISPR1-inhbab

No data available

Phenotype

Phenotype resulting from CRISPR1-inhbab

No data available

Phenotype of all Fish created by or utilizing CRISPR1-inhbab

Phenotype	Fish	Conditions	Figures
female organism hypophysis fshb expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/+ (AB)	standard conditions	Fig 14 from Zhao et al., 2022
ovary tnfa expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/+ (AB)	standard conditions	Fig 13 from Zhao et al., 2022
ovary apoptotic, abnormal	inhbaa^umo27/umo27; inhbab^umo28/+ (AB)	standard conditions	Fig 13 from Zhao et al., 2022
ovary il6 expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/+ (AB)	standard conditions	Fig 13 from Zhao et al., 2022
ovary cyp19a1a expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/+ (AB)	standard conditions	Fig 14 from Zhao et al., 2022
female organism hypophysis fshb expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 14 from Zhao et al., 2022
ovarian follicle increased distance ovarian follicle, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 5 from Zhao et al., 2022
granulosa cell hypertrophic, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 5 from Zhao et al., 2022
oocyte stage III decreased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 7 from Zhao et al., 2022
female organism developmental process involved in reproduction delayed, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 3 , Fig 4 from Zhao et al., 2022
ovarian follicle ovarian follicle development disrupted, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 3 from Zhao et al., 2022
ovarian follicle stage II absent, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 3 from Zhao et al., 2022
ovarian follicle development disrupted, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 6 from Zhao et al., 2022
ovary stromal cell increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 6 , Fig 7 , Fig 8 from Zhao et al., 2022
oocyte stage II absent, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 6 from Zhao et al., 2022
female organism decreased fecundity, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 7 from Zhao et al., 2022
ovarian follicle atretic, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 5 , Fig 8 from Zhao et al., 2022
ovarian follicle degeneration, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 5 , Fig 8 from Zhao et al., 2022
oocyte stage III absent, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 6 from Zhao et al., 2022
female organism decreased length, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 7 from Zhao et al., 2022
oocyte stage I increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 4 , Fig 7 from Zhao et al., 2022
whole organism dead, exacerbated	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 1 from Zhao et al., 2022
ovary cyp19a1a expression increased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 14 from Zhao et al., 2022
granulosa cell layer hypertrophic, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 5 from Zhao et al., 2022
oocyte stage II decreased amount, abnormal	inhbaa^umo27/umo27; inhbab^umo28/umo28 (AB)	standard conditions	Fig 4 , Fig 7 from Zhao et al., 2022
oocyte stage III decreased amount, abnormal	inhbb^umo29/umo29; inhbab^umo28/+ (AB)	standard conditions	Fig 12 from Zhao et al., 2022
oocyte stage II increased amount, abnormal	inhbb^umo29/umo29; inhbab^umo28/+ (AB)	standard conditions	Fig 12 from Zhao et al., 2022
oocyte stage III decreased amount, abnormal	inhbb^umo29/umo29; inhbab^umo28/umo28 (AB)	standard conditions	Fig 12 from Zhao et al., 2022
oocyte stage II increased amount, abnormal	inhbb^umo29/umo29; inhbab^umo28/umo28 (AB)	standard conditions	Fig 12 from Zhao et al., 2022
whole organism dead, exacerbated	inhbaa^umo27/umo27; inhbb^umo29/umo29; inhbab^umo28/umo28 (AB)	standard conditions	Fig 1 from Zhao et al., 2022

Citations