CRISPR

CRISPR1-smyd4

ID

ZDB-CRISPR-181129-6

Name

CRISPR1-smyd4

Previous Names

smyd4-SET-1 (1)

Target

smyd4 (1)

Sequence

5' - GGAGCGTCAGCGCCTCCTGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3020	smyd4

Expression

Gene expression in Wild Types + CRISPR1-smyd4

No data available

Phenotype

Phenotype resulting from CRISPR1-smyd4

No data available

Phenotype of all Fish created by or utilizing CRISPR1-smyd4

Phenotype	Fish	Conditions	Figures
determination of heart left/right asymmetry disrupted, abnormal	smyd4^zf3020/+; zf2036Tg	standard conditions	Fig. S2 from Xiao et al., 2018
cardiac ventricle hypoplastic, abnormal	smyd4^zf3020/+; zf2036Tg	standard conditions	Fig. S2 from Xiao et al., 2018
cardiac ventricle cardiac muscle cell decreased amount, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 , Fig. S3 from Xiao et al., 2018
histone methyltransferase activity decreased process quality, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 5 from Xiao et al., 2018
determination of heart left/right asymmetry disrupted, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 , Fig. S2 from Xiao et al., 2018
whole organism H3K4Me3 decreased amount, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 5 from Xiao et al., 2018
pericardium edematous, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 from Xiao et al., 2018
cardiac ventricle hypoplastic, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 , Fig. S2 from Xiao et al., 2018
cardiac muscle cell cell population proliferation decreased occurrence, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 4 , Fig. S4 from Xiao et al., 2018
heart trabecula morphogenesis disrupted, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 from Xiao et al., 2018
compact layer of ventricle increased thickness, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 4 from Xiao et al., 2018
heart looping disrupted, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 from Xiao et al., 2018
blood accumulation ventral aorta, abnormal	smyd4^{zf3020/zf3020}; zf2036Tg	standard conditions	Fig. 3 from Xiao et al., 2018

Citations