CRISPR

CRISPR1-shank3b

ID
ZDB-CRISPR-180829-1
Name
CRISPR1-shank3b
Previous Names
None
Target
Sequence
5' - GGGCGTGTTGTTGCCACGGCCGG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
fdu201 shank3b
zf3786 shank3b
Expression
Gene expression in Wild Types + CRISPR1-shank3b
No data available
Phenotype
Phenotype resulting from CRISPR1-shank3b
No data available
Phenotype of all Fish created by or utilizing CRISPR1-shank3b
Phenotype Fish Conditions Figures
locomotion decreased occurrence, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 3 from Liu et al., 2018
thigmotaxis process quality, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 4 with image from Liu et al., 2018
post-vent region bent, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 2 with image from Liu et al., 2018
embryo development delayed, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 2 with image from Liu et al., 2018
brain Ab3-homer1 labeling decreased amount, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 7 from Liu et al., 2018
whole organism decreased life span, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 2 with image from Liu et al., 2018
brain Ab7-syp labeling decreased amount, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 7 from Liu et al., 2018
adult locomotory behavior process quality, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 4 with image from Liu et al., 2018
eye Melanin decreased amount, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 2 with image from Liu et al., 2018
brain increased size, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 2 with image from Liu et al., 2018
whole organism decreased velocity, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 4 with image from Liu et al., 2018
social behavior process quality, abnormal shank3bfdu201/fdu201 (TU) standard conditions Fig. 5 with image from Liu et al., 2018
locomotion decreased occurrence, abnormal shank3bfdu201/+ (TU) standard conditions Fig. 3 from Liu et al., 2018
central nervous system RFP expression decreased amount, abnormal shank3bfdu201/fdu201; fdu101Tg standard conditions Fig. 6 with image from Liu et al., 2018
neuron development disrupted, abnormal shank3bfdu201/fdu201; fdu101Tg standard conditions Fig. 6 with image from Liu et al., 2018
Citations