Genomic Feature
kgs2
- ID
- ZDB-ALT-201130-2
- Name
- kgs2
- Synonyms
-
- NPY-KO11 (1)
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Shiozaki Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 19: 20113628 - 20113638 (GRCz11) (1) Details
- Nucleotide change
- CCCCAAGCAGA/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 11 bp deleted (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
AGCTGTCAAAACATTTAAAGAAACAATTGTTGATTTCCTCTCGTCAGTAATTAATTTAATAAGGAAATTCACCAGTTCATTTTTGTAAGTACAAAATCACACCCTGCTGTTTCAACTCGTGAGAGAAACGCTTTTAAAGCACCGCGTAGGGCGCAGTTAATTAGAAACGCGGTGGGGTTTTATCTAAAGGATTAATACCTTGCTTCCGAAAAGAAAGAAAATGAACTATGTGATGTTTGTCCAGTCAACAGCTGCCGCAGTGCCACTTAAGAACATTTAAATGCTAAAACTGCAGTTCAAAATAAATTCATGGCGTTTTGAGGACAGAAACACTTGAGGAAGAATTTGAGACTACGCTAATATTACAAACGAGGAGCTCACCTCTGCCTTGTTATGAGGTTGATGTAGTGTCTTAGTGCTGAATAATACTTGGCGAGCTCCTCCGCAGGTGCGTCCTCTCCCGGGTTGTCGGGCTTTGTTGGATACCCTTCTGTGAGAGT
CCCCAAGCAGA/- CGAACAAGAGAAACGCGCACGCTGCCCAGCTCATCCACATCTTCATGTTTGGATTCATCTGCAATTAAACAAAGCAAACGTGTTTGTGCTGATGCGCAATTTATTGTTCCAAAAAGTGATAAAAATAAAAACTGTTGAATTATAGTGTGCAAAAATCTATAAATGATAGCGCTTCTGTCATTAAAAACTTAATACCGATGTTTAATAATACTAAAAGAAACATTCTGAAAGAATGCAATACTTTCTTAAAATATTGAAACAATTTCAATAAAGTGTCTAAACAAAGGAAAATAATATTTGAAAGGTTGAACTTACCAGTGAATGAGGTCTTGGAATTTTTTGAGGTCTTGATTGGAATTCTTGCTCTGTGGGTGTCGACTTCCCAGATTTTCTGCATTCAGAGTCGTGCGTCTTCTGGTTTTATACCTGTACTGCTCGTGCCATAAAGAGCAGAGCCCACGCGCAATTGCGCGCGACTCTTTTGATGCGCGCGAGCCCGC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| npykgs2/kgs2 | Homozygous | ♀+/- ♂+/- | 3 figures  from Shiozaki et al., 2020 | 2 figures from Shiozaki et al., 2020 |
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Supplemental Information
- Genotyping protocol
- None
- Kawabe, M., Nishida, T., Takahashi, R., Inui, A., Shiozaki, K. (2023) Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish. Frontiers in pharmacology. 14:11682291168229
- Kawabe, M., Nishida, T., Horita, C., Ikeda, A., Takahashi, R., Inui, A., Shiozaki, K. (2022) Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish. Frontiers in pharmacology. 13:905711
- Kawabe, M., Hayashi, A., Komatsu, M., Inui, A., Shiozaki, K. (2021) Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish. Neuropeptides. 87:102136
- Shiozaki, K., Kawabe, M., Karasuyama, K., Kurachi, T., Hayashi, A., Ataka, K., Iwai, H., Takeno, H., Hayasaka, O., Kotani, T., Komatsu, M., Inui, A. (2020) Neuropeptide Y deficiency induces anxiety-like behaviours in zebrafish (Danio rerio). Scientific Reports. 10:5913
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