Genomic Feature
uab105
- ID
- ZDB-ALT-180606-11
- Name
- uab105
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Gorelick Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 5: 35563055 - 35563064 (GRCz11) (1) Details
- Nucleotide change
- ACCTCCGCAC/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 10 bp deleted (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
GGTGAGGTGACGACCTTGCAGTGCAGCAACGCTTCTCGAGCGAACTTGACCGCGGATGTGCATGAGTTCGGCAGCCTGTCCGGGGACATTGCCAACCTGAGTTCAGAAGGTACAGCAGCGCAGACAGCACCGGATATGGACGGACCGCGAGCGGCTTCGTGCCAGTTTGAACAACTGTTGCCCGCGAGCATGACCCATTATGCCCACCCGGAGCTCGAAAACGGACCGAGCCATAGCTTCGTAAAATCCACATCAATGTCTGGAGAGTTTGCTGGTCCCATGGAGGATTACACGAATCTCTATAATGTCAGAATCAAGACCGAGATGATGCCCCGTGATCTGAATGACACCTGGGCGTACCCGCATAGGTACGCCGAGGACTCTAACGGCCACTACGGGCCTCCAAAGCAAAGGACACCTTATGCTACTGGCCACGAACCCCCGTTTATCTGTAACCCTTATGAATACGGCCGAAGTACTGCTCTGGTTCCGCGGGAGCG
ACCTCCGCAC/- GAGCAGTGGTACCCGGGTGGGATGCTGACCCGTCATCCGTACCCTAACGTGCCTGGCGTGAAAAACGAGATGGGCGAATGGATGGATGTAACATCGTTCACGGATGGCAGGTAAGAGGCGGCTCTGCTGCGTTTTGTTTGCTCTGCGCCACAACTGATTTATTTAGTTTAAAAGTTTATTTCCAGATCTGCACGCGCCCCTTAAAATTATACCGCGCGCATTTGCACCTCTCAAACGGGACAAGAGTTTTTTTCGACCTAAAGAAATGCTTATTTGCATTTATATTTACTCTCTGAGTGCATAACCGAAATGAATAATACACCGTGCACAGGGTATATAGAAAATAGTTAAACAAAAACATTTGGAGTACATACAATTTTTTAAGAGGGTTTTCAAAGCCAGGCATCTCCCAGACATATTTTCAGTCGCTCCGAGGACCTTTAGAATAATCATAAGTAAATTTTGATAAACGTGACAACTGTAATTAAACTATATATATA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| aruab105/uab105 (AB) | Homozygous | ♀+/- ♂+/- | 7 figures from Crowder et al., 2017 | Fig. 8 from Crowder et al., 2017 | |
| aruab105/+ (AB) | Heterozygous | Unknown | |||
| aruab105/+ (AB) | Heterozygous | ♀+/- ♂+/- | Fig. 2 from Crowder et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Zadmajid, V., Shahriar, S., Gorelick, D.A. (2024) Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos. Development (Cambridge, England). 151(23):
- Crowder, C.M., Lassiter, C.S., Gorelick, D.A. (2017) Nuclear androgen receptor regulates testes organization and oocyte maturation in zebrafish. Endocrinology. 159(2):980-993
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