Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-010827-9
Plessy, Charles
RIKEN Yokohama institute
Omics Science Center
Functional Genomics Technology Team
1-7-22 Suehiro-chô, Tsurumi-ku, Yokohama, Kanagawa, 230-0045
Japan
Phone: +81-(0)45-503-9222 Email: plessy@riken.jp
FAX: +81-(0)45-503-9216 URL: http://charles.plessy.org/picture_gallery/
Biography and Research Interests:

Image : Frontal view of a 24h -8.4ngn1:GFP transgenic fish. Nice view on the telencephalon (medial), and on the olfactory bulb (lateral). The dorsalmost structure is the pineal body.

Ph.D. Research Topic: Integration of spatial information by neurogenin1 in zebrafish neural plate.



Current Research Topic: Promotome profiling of large collections of small samples for systems biology.



Publications:
Plessy, C., Dickmeis, T., Chalmel, F., and Strähle, U. (2005) Enhancer sequence conservation between vertebrates is favoured in developmental regulator genes. Trends Genet.. 21(4):207-210
Blader, P., Lam, C.S., Rastegar, S., Scardigli, R., Nicod, J.C., Simplicio, N., Plessy, C., Fischer, N., Schuurmans, C., Guillemot, F., and Strähle, U. (2004) Conserved and acquired features of neurogenin1 regulation. Development. 131(22):5627-5637
Dickmeis, T., Plessy, C., Rastegar, S., Aanstad, P., Herwig, R., Chalmel, F., Fischer, N., and Strähle, U. (2004) Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Genome Res.. 14(2):228-238
Geling, A., Plessy, C., Rastegar, S., Strähle, U., and Bally-Cuif, L. (2004) Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary. Development. 131(9):1993-2006
Blader, P., Plessy, C., and Strähle, U. (2003) Multiple regulatory elements with spatially and temporally distinct activities control neurogenin1 expression in primary neurons of the zebrafish embryo. Mech. Dev.. 120(2):211-218
Dickmeis, T., Rastegar, S., Aanstad, P., Clark, M., Fischer, N., Plessy, C., Rosa, F., Korzh, V., Strähle, U. (2001) Expression of brain subtype creatine kinase in the zebrafish embryo. Mech. Dev.. 109(2):409-412

Non-Zebrafish Publications:

Van De Bor V, Heitzler P, Leger S, Plessy C, Giangrande A. Precocious expression of the glide/gcm glial-promoting factor in Drosophila induces neurogenesis. Genetics. 2002 Mar;160(3):1095-106. PMID: 11901125

The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group). The Transcriptional Landscape of the Mamalian Genome. Science 2005 Sep 2;309(5740):1559-63. PMID: 16141072

Carninci P, Sandelin A, Lenhard B, Katayama S, Shimokawa K, Ponjavic J, Semple CA, Taylor MS, Engstrom PG, Frith MC, Forrest AR, Alkema WB, Tan SL, Plessy C, Kodzius R, Ravasi T, Kasukawa T, Fukuda S, Kanamori-Katayama M, Kitazume Y, Kawaji H, Kai C, Nakamura M, Konno H, Nakano K, Mottagui-Tabar S, Arner P, Chesi A, Gustincich S, Persichetti F, Suzuki H, Grimmond SM, Wells CA, Orlando V, Wahlestedt C, Liu ET, Harbers M, Kawai J, Bajic VB, Hume DA, Hayashizaki Y. Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet. 2006 Jun;38(6):626-635. Epub 2006 Apr 28. PMID: 16645617

Gustincich S, Sandelin A, Plessy C, Katayama S, Simone R, Lazarevic D, Hayashizaki Y, Carninci P. J Physiol. 2006 Jul 20; PMID:16857706

Plessy C, Fagiolini M, Wagatsuma A, Harasawa N, Kuji T, Asaka-Oba A, Kanzaki Y, Fujishima S, Waki K, Nakahara H, Hensch TK, Carninci P. A resource for transcriptomic analysis in the mouse brain. PLoS ONE. 2008 Aug 20;3(8):e3012.
PMID: 18714383