Research
General Information
ZIRC
ZFIN: Gene: gsk3b
ZFIN ID: ZDB-GENE-990714-4

Gene Name:glycogen synthase kinase 3 beta
Gene Symbol: gsk3b
Previous Names: fk80d11, wu:fb68h05(1) , wu:fk80d11(1) , fb68h05, GSK-3[b](1)
Nomenclature History


GENE EXPRESSION:(current status)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Phenotype: (current status)
  Data: 7 figures from Lee et al., 2007
  Observed in: heart, heart looping, heart morphogenesis, heart valve, pectoral fin ... (all 6)
Knockdown reagent: MO1-gsk3b (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process heart looping (more)
Molecular Function ATP binding (more)
All GO Terms (7)

Protein Families, Domains and Sites:
  • InterPro:IPR000719 (1)
  • InterPro:IPR002290 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR017442 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    gsk3b Contained in [BAC] DKEY-32O22 (1)    (order this)
    gsk3b Encodes [EST] fb68h05 , fk80d11 (1)
    [cDNA] MGC:194027 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131381 (1) 2624 bp
    Genomic GenBank:CR759880 (1) 183450 bp
    Polypeptide UniProtKB:Q9IBD2 (1) 421 aa
    Sequence Clusters UniGene:107139 (1)
    All Sequence Information (13)

    OTHER  gsk3b  GENE / MARKER PAGES:

  • Entrez Gene:30654 (1)
  • VEGA:OTTDARG00000025874 (1)
  • Ensembl(Zv8):ENSDARG00000017803 (1)

  • MAPPING INFORMATION:
      LG:  9    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish gsk3b  9
    Human GSK3B  3 (q13.3)
  • OMIM:605004
  • Entrez Gene:2932
  • Orthology Details

    CITATIONS   (21)