Research
General Information
ZIRC
ZFIN: Gene: wnt11
ZFIN ID: ZDB-GENE-990603-12

Gene Name:wingless-type MMTV integration site family, member 11
Gene Symbol: wnt11
Previous Names: slb, cb748(1) , silberblick
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 30 figure(s) from 17 publications
Directly submitted expression data: 7 figure(s) (64 images) from Thisse et al., 2001 [cb748]
  6 figure(s) (16 images) from Thisse et al., 2005 [eu266]
Wild Type Stages, Structures: Blastula:Sphere (4.00h-4.33h) to Hatching:Long-pec (48.00h-60.00h)
  adaxial cell, EVL ... (all 23)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   16 genotypes
Allele(s):   tx226, tz216, u148, unspecified_wnt11
Phenotype: (current status)
  Data: 15 figures from 12 publications
  Observed in: axial mesoderm, axis, brain, camera-type eye morphogenesis, cell migration involved in gastrulation ... (all 26)
Knockdown reagents: MO1-wnt11 (1) ,   MO2-wnt11 (1) ,   MO3-wnt11 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function signal transducer activity
Biological Process Wnt receptor signaling pathway (more)
Cellular Component plasma membrane (more)
All GO Terms (21)

Protein Families, Domains and Sites:
  • InterPro:IPR005816 (1)
  • InterPro:IPR005817 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    wnt11 Contained in [BAC] CH73-223D24 (1)    (order this)
    wnt11 Contains [SNP] rs3727880 (1)
    wnt11 Encodes [EST] cb748 (1)    (order this) , eu266 (1)
    [cDNA] MGC:193977 (1)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001144804 (1) 2132 bp
    Genomic GenBank:CU571324 (1) 101744 bp
    Polypeptide UniProtKB:O73864 (1) 354 aa
    Sequence Clusters UniGene:75830 (1)
    All Sequence Information (15)

    OTHER  wnt11  GENE / MARKER PAGES:

  • Entrez Gene:791595 (1)
  • VEGA:OTTDARG00000029156 (1)
  • Ensembl(Zv8):ENSDARG00000004256 (1)

  • MAPPING INFORMATION:
      LG:  5    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt11  5
    Human WNT11  11 (q13.5)
  • OMIM:603699
  • Entrez Gene:7481
  • Mouse Wnt11  7 (48.00 cM)
  • MGI:101948
  • Entrez Gene:22411
  • Orthology Details

    CITATIONS   (83)