Gene
emx2
- ID
- ZDB-GENE-990415-54
- Name
- empty spiracles homeobox 2
- Symbol
- emx2 Nomenclature History
- Previous Names
-
- fk69b03
- wu:fk69b03 (1)
- zgc:109855
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in brain development and vestibular receptor cell stereocilium organization. Predicted to localize to nucleus. Is expressed in several structures, including midbrain neural tube; nervous system; periderm; pharyngeal arch; and presumptive diencephalon. Orthologous to human EMX2 (empty spiracles homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 41 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109855 (15 images)
- eu131 (16 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Schizencephaly | 269160 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Helix-turn-helix motif | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:A0A8M9QF78
|
176 | |||||
UniProtKB:Q568U8
|
247 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-emx2 | polyclonal | Rabbit |
|
Trans Genic, Inc.
|
7 |
Plasmids
No data available