ZFIN ID: ZDB-GENE-990415-54
Gene Name: empty spiracles homeobox 2
Gene Symbol: emx2
Sequence Ontology ID : SO:0000704

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Previous Names: fk69b03, wu:fk69b03 (1), zgc:109855

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 30 figures from 16 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2005 [eu131]
  6 figures (15 images) from Thisse et al., 2004 [MGC:109855]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 4 (96.0h-120.0h)
  alar plate midbrain region, basal plate midbrain region, choroidal fissure, diencephalon (all 28) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
el586 Small Deletion Unknown Unknown TALEN
idc5 Small Deletion Unknown Unknown CRISPR
Targeting reagents: CRISPR1-emx2 (1), CRISPR2-emx2 (1), MO1-emx2 (1), MO2-emx2 (1), MO3-emx2 (1) (all 6) expand
PHENOTYPE
Data: 2 figures from Jiang et al., 2017
Observed in: lateral crista stereocilium bundle, lateral crista vestibular receptor cell stereocilium organization, lateral crista, macula utricle stereocilium bundle (all 12) expand
DISEASE ASSOCIATED WITH emx2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Schizencephaly 269160
GENE ONTOLOGY
Ontology GO Term
Biological Process vestibular receptor cell stereocilium organization (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA emx2-001 (1) 1986
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-emx2 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM emx2
    tg(myo6b:emx2-2a-nls-mcherry)
    MARKER RELATIONSHIPS
    emx2Contained in: [BAC] CH211-79E7 (1) (order this)
    emx2Encodes: [EST] eu131 (1), fk69b03
    [cDNA] MGC:109855 (1) (order this), MGC:192278 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131280 (1) 1614bp
    Genomic GenBank:AL929298 (1) 178487bp
    Select Tool
    Polypeptide UniProtKB:Q568U8 (1) 247aa
    Sequence Clusters UniGene:75105 (1)
    Sequence Information (all 21)
    OTHER emx2 GENE PAGES
  • Alliance (1)
  • Gene:30537 (1)
  • VEGA:OTTDARG00000020689 (1)
  • Ensembl(GRCz10):ENSDARG00000039701 (1)
  • ORTHOLOGY for emx2 (Chr: 13)
    CITATIONS (50)