Research
General Information
ZIRC
ZFIN: Gene: wnt5b
ZFIN ID: ZDB-GENE-980526-87

Gene Name:wingless-type MMTV integration site family, member 5b
Gene Symbol: wnt5b
Previous Names: ZfWnt5(2) , CHUNP6928, pipetail(1) , wu:fk85g06, id:ibd5111, wnt5a, ppt, wnt[b](1) , wnt5, Zwnt[b](1) , pipe tail
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 25 figure(s) from 17 publications
Directly submitted expression data: 6 figure(s) (17 images) from Thisse et al., 2005 [eu891]
  3 figure(s) (3 images) from Kudoh et al., 2001 [ibd5111]
Wild Type Stages, Structures: Cleavage:16-cell (1.50h-1.75h) to Hatching:Long-pec (48.00h-60.00h)
  axial mesoderm, dorsal fin ... (all 18)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   26 genotypes
Allele(s):   hi1780bTg, hi2735bTg, sk13, ta98, tc271b ... (all 9)
Phenotype: (current status)
  Data: 42 figures from 19 publications
  Observed in: angiogenesis, anterior cerebral vein, axis, cartilage morphogenesis, cell ... (all 42)
Knockdown reagents: MO1-wnt5b (1) ,   MO2-wnt5b (1) ,   MO3-wnt5b (1) ,   MO4-wnt5b (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process Wnt receptor signaling pathway, calcium modulating pathway (more)
Cellular Component extracellular region (more)
Molecular Function receptor binding (more)
All GO Terms (21)

Protein Families, Domains and Sites:
  • InterPro:IPR005816 (1)
  • InterPro:IPR005817 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • Loading Transcript Data...

    Gene Product Description


    CONSTRUCTS WITH SEQUENCE FROM wnt5b:
    Tg(hsp70l:wnt5b-GFP)

    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    wnt5b Contained in [BAC] CH73-211C7 (1)    (order this) , CH211-281K12 (1)    (order this) , DKEY-85M15 (1)    (order this)
    wnt5b Encodes [EST] eu891 (1) , fk85g06 , ibd5111 (1)    (order this)
    [STS] chunp6928
    [cDNA] MGC:194419 (1)    (order this) , MGC:194422 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130937 (1) 1730 bp
    Genomic GenBank:BX649324 (1) 218137 bp
    Polypeptide UniProtKB:B3DI33 (1) 363 aa
    Sequence Clusters UniGene:389 (1)
    All Sequence Information (19)

    OTHER  wnt5b  GENE / MARKER PAGES:

  • Entrez Gene:30105 (1)
  • VEGA:OTTDARG00000023607 (1)
  • Ensembl(Zv8):ENSDARG00000034894 (1)

  • MAPPING INFORMATION:
      LG:  4    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt5b  4
    Human WNT5B  12 (p13.3)
  • OMIM:606361
  • Entrez Gene:81029
  • Mouse Wnt5b  Unknown
  • MGI:98959
  • Entrez Gene:22419
  • Fruit fly Wnt5  X
  • FLYBASE:FBgn0010194
  • Orthology Details

    CITATIONS   (72)