ZFIN ID: ZDB-GENE-980526-87
Gene Name: wingless-type MMTV integration site family, member 5b
Gene Symbol: wnt5b
Previous Names: wnt5, wnt5a, wnt[b] (1), ZfWnt5 (2), Zwnt[b] (1), CHUNP6928, id:ibd5111, pipe tail, pipetail (1), ppt, wu:fk85g06
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 38 figures from 29 publications
Directly Submitted Expression Data: 3 figures (3 images) from Kudoh et al., 2001 [ibd5111]
  6 figures (17 images) from Thisse et al., 2005 [eu891]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Hatching:Long-pec (48.0h-60.0h)
  anatomical structure, axial mesoderm, dorsal fin, endoderm (all 23) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
hi1780bTg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2735bTg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015530Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024747Tg Transgenic Insertion DNA
    la029041Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sk13 Point Mutation ENU
    ta98 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc271b Unknown ENU
    te1c Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • th278 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti265 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • wnt5b_unspecified Unspecified
    Targeting reagents: MO1-wnt5b (1), MO2-wnt5b (1), MO3-wnt5b (1), MO4-wnt5b (1)
    PHENOTYPE
    Data: 62 figures from 28 publications
    Observed in: angiogenesis, anterior cerebral vein, anterior commissure astrocyte, anterior commissure commissural neuron axon guidance (all 86) expand
    DISEASE ASSOCIATED WITH wnt5b HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process Wnt signaling pathway, calcium modulating pathway (more)
    Cellular Component extracellular region (more)
    Molecular Function receptor binding (more)
    GO Terms (all 31)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR018161 (1)
  • InterPro:IPR026537 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt5b-003 (1) 2049
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-wnt5b (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt5b
    Tg(hsp70l:wnt5b-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    wnt5bContained in: [BAC] CH73-211C7 (1) (order this), CH211-281K12 (1) (order this), DKEY-85M15 (1) (order this)
    wnt5bEncodes: [EST] eu891 (1), fk85g06, ibd5111 (1) (order this)
    [STS] chunp6928
    [cDNA] MGC:194419 (1) (order this), MGC:194422 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130937 (1) 1730bp
    Genomic GenBank:BX649324 (1) 218137bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DI33 (1) 363aa
    Sequence Clusters UniGene:389 (1)
    Sequence Information (all 29)
    OTHER wnt5b GENE PAGES 
  • Gene:30105 (1)
  • VEGA:OTTDARG00000023607 (1)
  • Ensembl(GRCz10):ENSDARG00000102464 (1)
  • ORTHOLOGY for wnt5b (Chr: 4) 
    Species Symbol Chromosome Accession # Evidence
    Human WNT5B 12
  • Gene:81029
  • OMIM:606361
  • HGNC:16265
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Wnt5b 6
  • MGI:98959
  • Gene:22419
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Fruit fly Wnt5 X
  • FLYBASE:FBgn0010194
  • Gene:32838
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (126)