ZFIN ID: ZDB-GENE-980526-352

Gene Name:wingless-type MMTV integration site family, member 4a
Gene Symbol: wnt4a

Previous Names: zgc:136737, wnt4, ZfWnt4(1)
Nomenclature History

---

GENE EXPRESSION:(current status)

All expression data:	13 figure(s) from 7 publications
Directly submitted expression data:	6 figure(s) (12 images) from Thisse et al., 2005 [eu648]
Wild Type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.00h-60.00h)
	alar plate midbrain region, diencephalon ... (all 19)
Curated microarray expression:	GEO  (1)

---

MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   3 genotypes
Allele(s):   fh294, fh295, unrec_wnt4a

Phenotype: (current status)

Data:	1 figure from Hendricks et al., 2008
Observed in:	habenular commissure

Knockdown reagents: MO1-wnt4a (1) ,   MO2-wnt4a (1) ,   MO3-wnt4a (1)

---

GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Molecular Function	signal transducer activity
Biological Process	heart development (more)
Cellular Component	extracellular region (more)

All GO Terms (9)

Protein Families, Domains and Sites:

InterPro:IPR005816 (1) InterPro:IPR005817 (1) InterPro:IPR009142 (1) InterPro:IPR018161 (1)

PROSITE:PS00246 (1)

Pfam:PF00110 (1)

Gene Product Description

---

SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

wnt4a Contained in	[BAC] DKEY-208K8 (1)    (order this)
wnt4a Contains	[SNP] rs3728403 (1)
wnt4a Encodes	[EST] eu648 (1) [cDNA] MGC:136737 (1)    (order this) , MGC:194977 (1)    (order this) , MGC:194994 (1)    (order this)

---

SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001040387 (1)	2264 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR926911 (1)	158622 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:P47793 (1)	352 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:385 (1)
All Sequence Information (16)

---

OTHER  wnt4a  GENE / MARKER PAGES:

Entrez Gene:30123 (1)

VEGA:OTTDARG00000027690 (1)

Ensembl(Zv8):ENSDARG00000071208 (1)

---

MAPPING INFORMATION:

LG:  11  Details

View Map: Merged  Individual Panels

---

ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CE
Zebrafish	wnt4a	11
Mouse	Wnt4	4 (syntenic)	MGI:98957 Entrez Gene:22417
Orthology Details

---

CITATIONS   (27)