Gene

dab2ipa

ID

ZDB-GENE-081104-516

Name

DAB2 interacting protein a

Symbol

dab2ipa Nomenclature History

Previous Names

si:dkey-83f4.1

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in several processes, including negative regulation of angiogenesis; negative regulation of vascular endothelial growth factor receptor signaling pathway; and reelin-mediated signaling pathway. Orthologous to human DAB2IP (DAB2 interacting protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhong et al., 2018

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dab2ipa Human Ortholog

No data available

Associated With dab2ipa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023152	Ras GTPase-activating protein, conserved site
Domain	IPR000008	C2 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR001936	Ras GTPase-activating domain
Domain	IPR021887	Disabled homolog 2-interacting protein, C-terminal domain
Family	IPR039360	Ras GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Length	C2 domain	C2 domain superfamily	Disabled homolog 2-interacting protein, C-terminal domain	PH-like domain superfamily	Pleckstrin homology domain	Ras GTPase-activating domain	Ras GTPase-activating protein	Ras GTPase-activating protein, conserved site	Rho GTPase activation protein
UniProtKB:A0A8M3B4Q7 InterPro	1162
UniProtKB:A0A8M3AUY3 InterPro	1255
UniProtKB:A0A8M3B1U1 InterPro	1069
UniProtKB:A0A8M6YZX5 InterPro	1256

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dab2ipa-203 (1) Ensembl	Havana	3443 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dab2ipa-002 (1) Ensembl	Havana	539 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations