ZFIN is now using GRCz12tu for Genomic Data
Gene
atp2b1b
- ID
- ZDB-GENE-080409-1
- Name
- ATPase plasma membrane Ca2+ transporting 1b
- Symbol
- atp2b1b Nomenclature History
- Previous Names
-
- pmca1b (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP binding activity; ATP hydrolysis activity; and P-type calcium transporter activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in plasma membrane. Is expressed in blood; eye; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 66. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 66 | Alliance | Intellectual developmental disorder, autosomal dominant 66 | 619910 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004014 | Cation-transporting P-type ATPase, N-terminal |
| Domain | IPR006068 | Cation-transporting P-type ATPase, C-terminal |
| Domain | IPR022141 | Plasma membrane calcium transporting P-type ATPase, C-terminal |
| Domain | IPR044492 | P-type ATPase, haloacid dehalogenase domain |
| Domain | IPR059000 | P-type ATPase, A domain |
| Family | IPR001757 | P-type ATPase |
| Family | IPR006408 | P-type ATPase, subfamily IIB |
| Homologous_superfamily | IPR008250 | P-type ATPase, A domain superfamily |
| Homologous_superfamily | IPR023214 | HAD superfamily |
| Homologous_superfamily | IPR023298 | P-type ATPase, transmembrane domain superfamily |
| Homologous_superfamily | IPR023299 | P-type ATPase, cytoplasmic domain N |
| Homologous_superfamily | IPR036412 | HAD-like superfamily |
| PTM | IPR018303 | P-type ATPase, phosphorylation site |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cation-transporting P-type ATPase, C-terminal | Cation-transporting P-type ATPase, N-terminal | HAD-like superfamily | HAD superfamily | Plasma membrane calcium transporting P-type ATPase, C-terminal | P-type ATPase | P-type ATPase, A domain | P-type ATPase, A domain superfamily | P-type ATPase, cytoplasmic domain N | P-type ATPase, haloacid dehalogenase domain | P-type ATPase, phosphorylation site | P-type ATPase, subfamily IIB | P-type ATPase, transmembrane domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B2CZB7 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0A8M3APN2 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0A8M9PUY9 | InterPro | 896 | |||||||||||||
| UniProtKB:A0AB32THH2 | InterPro | 1251 | |||||||||||||
| UniProtKB:A0AC58IVG9 | InterPro | 1251 | |||||||||||||
| UniProtKB:A0AC58IVH0 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0AC58IVH1 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0AC58IVH2 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0AC58IVH3 | InterPro | 1251 | |||||||||||||
| UniProtKB:A0AC58IVH8 | InterPro | 1240 | |||||||||||||
| UniProtKB:A0AC58IVI0 | InterPro | 979 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atp2b1b-201
(1)
|
Ensembl | 4,711 nt | ||
| mRNA |
atp2b1b-202
(1)
|
Ensembl | 744 nt | ||
| mRNA |
atp2b1b-203
(1)
|
Ensembl | 1,292 nt | ||
| mRNA |
atp2b1b-204
(1)
|
Ensembl | 765 nt | ||
| mRNA |
atp2b1b-205
(1)
|
Ensembl | 647 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers