Gene
sirt3
- ID
- ZDB-GENE-070112-1762
- Name
- sirtuin 3
- Symbol
- sirt3 Nomenclature History
- Previous Names
-
- zgc:158774
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have NAD+ binding activity and NAD-dependent histone deacetylase activity. Predicted to localize to cytoplasm and nucleus. Is expressed in liver and retina. Orthologous to human SIRT3 (sirtuin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Sheng et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR026590 | Sirtuin family, catalytic core domain |
| Family | IPR003000 | Sirtuin family |
| Family | IPR017328 | Sirtuin, class I |
| Homologous_superfamily | IPR026591 | Sirtuin, catalytic core small domain superfamily |
| Homologous_superfamily | IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | Sirtuin, catalytic core small domain superfamily | Sirtuin, class I | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B4G2
|
253 | |||||
|
UniProtKB:A0A2R8QMP7
|
358 | |||||
|
UniProtKB:A0A8M6Z7Q0
|
204 | |||||
|
UniProtKB:A1L2B7
|
357 |
Interactions and Pathways
No data available
Plasmids
No data available