ptk6b

ID

ZDB-GENE-060929-1150

Name

PTK6 protein tyrosine kinase 6b

Symbol

ptk6b Nomenclature History

Previous Names

zgc:153964 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation and cell surface receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in plasma membrane. Orthologous to human PTK6 (protein tyrosine kinase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Yang et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptk6b Human Ortholog

No data available

Associated With ptk6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR000980	SH2 domain
Domain	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain	IPR001452	SH3 domain
Domain	IPR020635	Tyrosine-protein kinase, catalytic domain
Family	IPR050198	Non-receptor tyrosine kinases involved in cell signaling
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR036860	SH2 domain superfamily