Gene
itgb1a
- ID
- ZDB-GENE-060803-2
- Name
- integrin, beta 1a
- Symbol
- itgb1a Nomenclature History
- Previous Names
-
- beta1-1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Exhibits fibronectin binding activity and protein heterodimerization activity. Involved in positive regulation of sprouting angiogenesis. Predicted to localize to cell surface; focal adhesion; and integrin complex. Is expressed in several structures, including cardiovascular system; integument; liver; periderm; and pleuroperitoneal region. Orthologous to human ITGB1 (integrin subunit beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR002369 | Integrin beta subunit, VWA domain |
Domain | IPR012896 | Integrin beta subunit, tail |
Domain | IPR013111 | EGF-like domain, extracellular |
Domain | IPR014836 | Integrin beta subunit, cytoplasmic domain |
Domain | IPR016201 | PSI domain |
Domain | IPR033760 | Integrin beta N-terminal |
Domain | IPR040622 | Integrin beta, epidermal growth factor-like domain 1 |
Family | IPR015812 | Integrin beta subunit |
Homologous_superfamily | IPR032695 | Integrin domain superfamily |
Homologous_superfamily | IPR036349 | Integrin beta tail domain superfamily |
Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
Protein | Length | EGF-like domain, extracellular | Integrin beta, epidermal growth factor-like domain 1 | Integrin beta N-terminal | Integrin beta subunit | Integrin beta subunit, cytoplasmic domain | Integrin beta subunit, tail | Integrin beta subunit, VWA domain | Integrin beta tail domain superfamily | Integrin domain superfamily | PSI domain | von Willebrand factor A-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M6YW86
|
802 | |||||||||||
UniProtKB:F1QG85
|
798 | |||||||||||
UniProtKB:Q3YAA1
|
798 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
itgb1a-201
(1)
|
Havana | 3414 nt | |
mRNA |
itgb1a-202
(1)
|
Ensembl | 6015 nt |
Interactions and Pathways
No data available
Plasmids
No data available