Gene

osbp2b

ID

ZDB-GENE-060526-3

Name

oxysterol binding protein 2b

Symbol

osbp2b Nomenclature History

Previous Names

si:ch211-106a19.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have cholesterol binding activity and sterol transporter activity. Predicted to be involved in lipid transport. Predicted to localize to cytosol; intracellular membrane-bounded organelle; and membrane. Orthologous to human OSBP2 (oxysterol binding protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With osbp2b Human Ortholog

No data available

Associated With osbp2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018494	Oxysterol-binding protein, conserved site
Domain	IPR001849	Pleckstrin homology domain
Family	IPR000648	Oxysterol-binding protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR037239	Oxysterol-binding protein superfamily

Domain Details Per Protein

Protein	Length	Oxysterol-binding protein	Oxysterol-binding protein, conserved site	Oxysterol-binding protein superfamily	PH-like domain superfamily	Pleckstrin homology domain
UniProtKB:A2BEG1 InterPro	808
UniProtKB:A0A8M9PXS1 InterPro	463
UniProtKB:A0A8M3AS31 InterPro	555
UniProtKB:A0A8M9Q8S0 InterPro	822
UniProtKB:A0A8M9PKA3 InterPro	708

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:ch211-106a19.1-201 (1) Ensembl	Ensembl	2,530 nt	Select Tool
mRNA	si:ch211-106a19.1-204 (1) Ensembl	Ensembl	745 nt	Select Tool
ncRNA	si:ch211-106a19.1-002 (1) Ensembl	Ensembl	670 nt	Select Tool
ncRNA	si:ch211-106a19.1-004 (1) Ensembl	Ensembl	434 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations