Gene
slc39a14
- ID
- ZDB-GENE-060315-2
- Name
- solute carrier family 39 member 14
- Symbol
- slc39a14 Nomenclature History
- Previous Names
-
- ZIP14 (1)
- sb:cb823
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have manganese ion transmembrane transporter activity and zinc ion transmembrane transporter activity. Involved in manganese ion homeostasis. Localizes to plasma membrane. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 2. Is expressed in neurogenic placode; notochord; presumptive telencephalon; pronephric duct; and somite. Orthologous to human SLC39A14 (solute carrier family 39 member 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb823 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypermanganesemia with dystonia 2 | Alliance | Hypermanganesemia with dystonia 2 | 617013 |
| ?Hyperostosis cranalis interna | 144755 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR003689 | Zinc/iron permease |
Domain Details Per Protein
| Protein | Length | Zinc/iron permease |
|---|---|---|
|
UniProtKB:A0A8M9Q926
|
494 | |
|
UniProtKB:A0A2R8Q9W7
|
494 | |
|
UniProtKB:A0A0G2KQY6
|
494 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available