Gene
ets2
- ID
- ZDB-GENE-050522-552
- Name
- v-ets avian erythroblastosis virus E26 oncogene homolog 2
- Symbol
- ets2 Nomenclature History
- Previous Names
-
- wu:fe02h08
- wu:fk74c05
- zgc:92106
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in anterior lateral plate mesoderm; endothelial cell; head; lateral plate mesoderm; and pharyngeal arch 3-7. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000418 | Ets domain |
| Domain | IPR003118 | Pointed domain |
| Domain | IPR045688 | Ets1, N-terminal flanking region of Ets domain |
| Family | IPR016311 | Transforming protein C-ets |
| Family | IPR046328 | ETS family |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Ets1, N-terminal flanking region of Ets domain | Ets domain | ETS family | Pointed domain | Sterile alpha motif/pointed domain superfamily | Transforming protein C-ets | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q501S1
|
439 |
Interactions and Pathways
No data available
Plasmids