enpep

ID

ZDB-GENE-050309-218

Name

glutamyl aminopeptidase

Symbol

enpep Nomenclature History

Previous Names

im:7152184
si:ch211-146m5.2

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to be located in membrane. Predicted to be active in cytoplasm; extracellular space; and plasma membrane. Is expressed in endoderm; gut; intestinal bulb; pronephric duct; and pronephros. Orthologous to human ENPEP (glutamyl aminopeptidase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7152184 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With enpep Human Ortholog

No data available

Associated With enpep Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR014782	Peptidase M1, membrane alanine aminopeptidase
Domain	IPR024571	ERAP1-like C-terminal domain
Domain	IPR045357	Aminopeptidase N-like , N-terminal domain
Family	IPR001930	Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family	IPR034016	Aminopeptidase N-type
Family	IPR050344	Peptidase M1 family aminopeptidases
Homologous_superfamily	IPR027268	Peptidase M4/M1, CTD superfamily
Homologous_superfamily	IPR042097	Aminopeptidase N-like , N-terminal domain superfamliy