Gene

ddr2l

ID
ZDB-GENE-041210-162
Name
discoidin domain receptor family, member 2, like
Symbol
ddr2l Nomenclature History
Previous Names
  • ddr2
  • ddr2b
  • ddr2c (1)
  • si:ch211-193c2.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable collagen binding activity and protein tyrosine kinase collagen receptor activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of neuron projection development; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Challa et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa13982Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
1 - 1 of 1
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Sequence Targeting Reagents
No data available
Human Disease
Associated With ddr2l Human Ortholog
No data available
Associated With ddr2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Conserved_site IPR002011 Tyrosine-protein kinase, receptor class II, conserved site
Domain IPR000421 Coagulation factor 5/8, C-terminal domain
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
1 - 5 of 10 Show all
Domain Details Per Protein
Protein Additional Resources Length Coagulation factor 5/8, C-terminal domain Discoidin domain-containing receptor 1/2, DS-like domain Galactose-binding-like domain superfamily Protein kinase domain Protein kinase-like domain superfamily Receptor Tyrosine Kinase Serine-threonine/tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase, active site Tyrosine-protein kinase, catalytic domain Tyrosine-protein kinase, receptor class II, conserved site
UniProtKB:A0A8N7T7R5 InterPro 873
UniProtKB:A0A8M9PQU9 InterPro 873
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ddr2l-201 (1)
Ensembl
Ensembl 2,883 nt
ZFIN BLAST
mRNA ddr2l-202 (1)
Ensembl
Ensembl 2,654 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-126P21ZFIN Curated Data
Contained inBACCH211-193C2ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_688610 (1)3820 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CU655815 (1)162765 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M9PQU9 (1)873 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
TSV
1 - 2 of 2
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