Gene
sirt4
- ID
- ZDB-GENE-041010-65
- Name
- sirtuin 4
- Symbol
- sirt4 Nomenclature History
- Previous Names
-
- im:7139453
- zgc:103539 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable deacetylase activity. Predicted to be involved in protein deacetylation. Predicted to be located in mitochondrial matrix. Is expressed in liver and retina. Orthologous to human SIRT4 (sirtuin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139453 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR026590 | Sirtuin family, catalytic core domain |
| Family | IPR003000 | Sirtuin family |
| Family | IPR026587 | Sirtuin, class II |
| Family | IPR050134 | NAD-dependent sirtuin protein deacylases |
| Homologous_superfamily | IPR026591 | Sirtuin, catalytic core small domain superfamily |
| Homologous_superfamily | IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | NAD-dependent sirtuin protein deacylases | Sirtuin, catalytic core small domain superfamily | Sirtuin, class II | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QHM6
|
310 | ||||||
|
UniProtKB:Q5XJ86
|
310 |
Interactions and Pathways
No data available
Plasmids
No data available