ZFIN is now using GRCz12tu for Genomic Data
Gene
cdhr1a
- ID
- ZDB-GENE-040924-4
- Name
- cadherin-related family member 1a
- Symbol
- cdhr1a Nomenclature History
- Previous Names
-
- cdhr1
- pcdh21
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cell adhesion molecule binding activity. Involved in retina layer formation. Acts upstream of or within glial cell development; photoreceptor cell development; and retina development in camera-type eye. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in photoreceptor cell and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in cone-rod dystrophy 15. Orthologous to human CDHR1 (cadherin related family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 15 | Alliance | Cone-rod dystrophy 15 | 613660 |
| cone-rod dystrophy 15 | Alliance | Macular dystrophy, retinal | 613660 |
| cone-rod dystrophy 15 | Alliance | Retinitis pigmentosa 65 | 613660 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9PXT0 | InterPro | 749 | |||
| UniProtKB:Q6B3P0 | InterPro | 857 | |||
| UniProtKB:G1K2I7 | InterPro | 855 | |||
| UniProtKB:A0AB32T349 | InterPro | 747 | |||
| UniProtKB:A0AC58H0U6 | InterPro | 855 | |||
| UniProtKB:A0AC58H0U8 | InterPro | 855 | |||
| UniProtKB:A0AC58H0U9 | InterPro | 855 | |||
| UniProtKB:A0AC58H0V2 | InterPro | 707 | |||
| UniProtKB:A0AC58H0V4 | InterPro | 815 | |||
| UniProtKB:A0AC58H0V6 | InterPro | 815 | |||
| UniProtKB:A0AC58H0V7 | InterPro | 815 | |||
| UniProtKB:A0AC58H0W1 | InterPro | 707 | |||
| UniProtKB:A0AC58H0W4 | InterPro | 815 | |||
| UniProtKB:A0AC58H0W5 | InterPro | 707 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdhr1a-201
(1)
|
Ensembl | 4,844 nt | ||
| mRNA |
cdhr1a-202
(1)
|
Ensembl | 3,862 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cdhr1a | polyclonal | IgG | Rabbit |
|
Boster Biological
|
2 |
Plasmids
No data available
- Genome Browsers