ZFIN ID: ZDB-GENE-040827-2

Gene Name:leucine rich repeat containing 6
Gene Symbol: lrrc6

Previous Names: unm tg238a, lrrc6l(1) , sea(1) , zar(1) , seahorse(1) , zator(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	5 figure(s) from 2 publications
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
	chordo neural hinge, floor plate ... (all 11)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   13 genotypes
Allele(s):   fa20r, hi3308Tg, tg238a

Phenotype: (current status)

Data:	14 figures from 4 publications
Observed in:	ciliary or flagellar motility, cilium, cilium movement involved in cell motility, cloacal chamber, convergent extension involved in gastrulation ... (all 26)

Knockdown reagents: MO1-lrrc6 (1) ,   MO2-lrrc6 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	convergent extension involved in gastrulation (more)
Cellular Component	cytoplasm
Molecular Function	protein binding

All GO Terms (12)

Protein Families, Domains and Sites:

InterPro:IPR003603 (1)

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ANTIBODIES:

Ab1-lrrc6 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

lrrc6 Contained in	[BAC] CH211-66B9 (1)    (order this) , DKEY-177E13 (1)    (order this)
lrrc6 Encodes	[cDNA] MGC:193911 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001002311 (1)	1758 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX511268 (1)	167067 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:B3DH20 (1)	440 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:80306 (1)
All Sequence Information (11)

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OTHER  lrrc6  GENE / MARKER PAGES:

Entrez Gene:432388 (1)

VEGA:OTTDARG00000019988 (1)

Ensembl(Zv8):ENSDARG00000053318 (1)

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MAPPING INFORMATION:

LG:  2    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	lrrc6	2
Human	LRRC6	8 (q24.22)	Entrez Gene:23639
Mouse	Lrrc6	15 (29.22 cM)	MGI:1859553 Entrez Gene:54562
Orthology Details

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CITATIONS   (21)