header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040827-2
Gene Name: leucine rich repeat containing 6
Gene Symbol: lrrc6    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: lrrc6l (1), sea (1), seahorse (1), unm tg238a, zar (1), zator (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Involved in several processes, including cilium movement involved in cell motility; embryonic morphogenesis; and motile cilium assembly. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 19. Is expressed in several structures, including floor plate; forerunner cell group; olfactory pit; pronephros; and tail bud. Orthologous to human LRRC6 (leucine rich repeat containing 6).
Genome Resources: Alliance (1),  Gene:432388 (1),  Ensembl(GRCz11):ENSDARG00000053318 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fa20r Point Mutation Exon 5 Premature Stop ENU
hi3308Tg Transgenic Insertion Intron 4 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • pd1087 Point Mutation Unknown Premature Stop ENU
    sa14388 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14481 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19848 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19849 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19850 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25885 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33003 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39914 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tg238a Point Mutation Exon 3 Missense
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lrrc6 N/A 2
    MO2-lrrc6 N/A 1
    MO3-lrrc6 N/A 1
    DISEASE ASSOCIATED WITH lrrc6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    primary ciliary dyskinesia 19 Alliance Ciliary dyskinesia, primary, 19 614935
    DISEASE ASSOCIATED WITH lrrc6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in gastrulation (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001611 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS51450 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lrrc6-202 (1)    Ensembl 1791
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-lrrc6 polyclonal IgG Rabbit IHC, WB Covance
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lrrc6 No data available
    MARKER RELATIONSHIPS
    lrrc6 Contained in: [BAC] CH211-66B9 (1) (order this), DKEY-177E13 (1) (order this)
    lrrc6 Encodes: [cDNA] MGC:193911 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002311 (1) 1758 bp
    Genomic GenBank:BX511268 (1) 167067 bp
    Select Tool
    Polypeptide UniProtKB:B3DH20 (1) 440 aa
    Sequence Clusters UniGene:80306 (1)
    Sequence Information (all 18)
    ORTHOLOGY for lrrc6 ( Chr: 2 )
    CITATIONS (41)