Gene

limk2

ID
ZDB-GENE-040718-398
Name
LIM domain kinase 2
Symbol
limk2 Nomenclature History
Previous Names
  • wu:fa97c09
  • wu:fk73e11
  • zgc:91990
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including axial vasculature; cephalic musculature; digestive system; mid cerebral vein; and nervous system. Orthologous to human LIMK2 (LIM domain kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Ott et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With limk2 Human Ortholog
No data available
Associated With limk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001478 PDZ domain
Domain IPR001781 Zinc finger, LIM-type
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length PDZ domain PDZ superfamily Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain Zinc finger, LIM-type
UniProtKB:Q6DG29 651
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations