Research
General Information
ZIRC
ZFIN: Gene: nrp1b
ZFIN ID: ZDB-GENE-040611-1

Gene Name:neuropilin 1b
Gene Symbol: nrp1b
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 5 figure(s) from 5 publications
Wild Type Stages, Structures: Segmentation:5-9 somites (11.66h-14.00h) to Larval:Protruding-mouth (72.00h-96.00h, 3.5mm)
  unspecified
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   3 genotypes
Allele(s):   fh278, fh279, unrec_nrp1b
Phenotype: (current status)
Knockdown reagents: MO1-nrp1b (1) ,   MO2-nrp1b (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function protein binding
Biological Process angiogenesis (more)
Cellular Component membrane
All GO Terms (6)

Protein Families, Domains and Sites:
  • InterPro:IPR000421 (1)
  • InterPro:IPR000859 (1)
  • InterPro:IPR000998 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR014648 (1)
  • PROSITE:PS01180 (1)
  • PROSITE:PS01285 (1)
  • PROSITE:PS01286 (1)
  • PROSITE:PS50022 (1)
  • PROSITE:PS50060 (1)
  • Pfam:PF00431 (1)
  • Pfam:PF00629 (1)
  • Pfam:PF00754 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    nrp1b Contained in [BAC] DKEY-218A22 (1)    (order this)
    nrp1b Encodes [cDNA] MGC:158182 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205674 (1) 4633 bp
    Genomic GenBank:BX088727 (1) 185178 bp
    Polypeptide UniProtKB:A3KNA2 (1) 959 aa
    Sequence Clusters UniGene:132331 (1)
    All Sequence Information (16)

    OTHER  nrp1b  GENE / MARKER PAGES:

  • Entrez Gene:402973 (1)
  • VEGA:OTTDARG00000019989 (1)
  • Ensembl(Zv8):ENSDARG00000027290 (1)

  • MAPPING INFORMATION:
      LG:  2    Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish nrp1b  2
    Human NRP1  10 (p12)
  • OMIM:602069
  • Entrez Gene:8829
  • Mouse Nrp1  8 (73.00 cM)
  • MGI:106206
  • Entrez Gene:18186
  • Orthology Details

    CITATIONS   (20)