Research
General Information
ZIRC
ZFIN: Gene: aacs
ZFIN ID: ZDB-GENE-040426-903

Gene Name:acetoacetyl-CoA synthetase
Gene Symbol: aacs
Previous Names: zgc:56105(1)
Nomenclature History


GENE EXPRESSION:(current status)
Directly submitted expression data: 7 figure(s) (13 images) from Thisse et al., 2004 [IMAGE:7149117]
  4 figure(s) (6 images) from Thisse et al., 2004 [IMAGE:7136547]
Wild Type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
  alar plate midbrain region, epiphysis ... (all 11)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Phenotype: (current status)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process fatty acid metabolic process (more)
Cellular Component cytoplasm
Molecular Function ATP binding (more)
All GO Terms (9)

Protein Families, Domains and Sites:
  • InterPro:IPR000873 (1)
  • InterPro:IPR005914 (1)
  • InterPro:IPR020845 (1)
  • PROSITE:PS00455 (1)
  • Pfam:PF00501 (1)
  • EC:6.2.1.16 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    aacs Contained in [BAC] DKEY-253H15 (1)    (order this)
    aacs Encodes [EST] IMAGE:7136547 (1)    (order this) , IMAGE:7149117 (1)    (order this)
    [cDNA] MGC:56105 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201009 (1) 2786 bp
    Genomic GenBank:CR759959 (1) 170133 bp
    Polypeptide UniProtKB:A3QK15 (1) 673 aa
    Sequence Clusters UniGene:25204 (1)
    All Sequence Information (10)

    OTHER  aacs  GENE / MARKER PAGES:

  • Entrez Gene:393984 (1)
  • VEGA:OTTDARG00000017407 (1)
  • Ensembl(Zv8):ENSDARG00000012468 (1)

  • MAPPING INFORMATION:
      LG:  5    Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish aacs  5
    Human AACS  12 (q24.31)
  • Entrez Gene:65985
  • Mouse Aacs  5 (syntenic)
  • MGI:1926144
  • Entrez Gene:78894
  • Orthology Details

    CITATIONS   (14)