Gene
clic5b
- ID
- ZDB-GENE-040426-2542
- Name
- chloride intracellular channel 5b
- Symbol
- clic5b Nomenclature History
- Previous Names
-
- clic5
- im:6907594
- zgc:77538
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have chloride channel activity and voltage-gated ion channel activity. Predicted to be involved in chloride transport; regulation of ion transmembrane transport; and sensory perception of sound. Predicted to localize to chloride channel complex and cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Is expressed in digestive system; immature eye; pronephric duct; and sensory system. Orthologous to human CLIC5 (chloride intracellular channel 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907594 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive nonsyndromic deafness 103 | Alliance | ?Deafness, autosomal recessive 103 | 616042 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR004045 | Glutathione S-transferase, N-terminal |
Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
Domain | IPR042069 | CLIC5, C-terminal GST domain |
Family | IPR002946 | Intracellular chloride channel |
Family | IPR040079 | Glutathione transferase family |
Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | CLIC5, C-terminal GST domain | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Glutathione transferase family | Intracellular chloride channel | Thioredoxin-like superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A2CEF5
|
243 | |||||||
UniProtKB:Q6NXB5
|
408 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
clic5b-201
(1)
|
Havana | 2237 nt | |
mRNA |
clic5b-202
(1)
|
Havana | 1003 nt |
Interactions and Pathways
No data available
Plasmids
No data available