Gene

clic5b

ID
ZDB-GENE-040426-2542
Name
chloride intracellular channel 5b
Symbol
clic5b Nomenclature History
Previous Names
  • clic5
  • im:6907594
  • zgc:77538
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have chloride channel activity and voltage-gated ion channel activity. Predicted to be involved in chloride transport; regulation of ion transmembrane transport; and sensory perception of sound. Predicted to localize to chloride channel complex and cytoplasm. Is expressed in digestive system; immature eye; pronephric duct; and sensory system. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Orthologous to human CLIC5 (chloride intracellular channel 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With clic5b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Deafness, autosomal recessive 103 616042
Associated With clic5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004045 Glutathione S-transferase, N-terminal
Domain IPR010987 Glutathione S-transferase, C-terminal-like
Domain IPR042069 CLIC5, C-terminal GST domain
Family IPR002946 Intracellular chloride channel
Family IPR040079 Glutathione transferase family
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Homologous_superfamily IPR036282 Glutathione S-transferase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length CLIC5, C-terminal GST domain Glutathione S-transferase, C-terminal domain superfamily Glutathione S-transferase, C-terminal-like Glutathione S-transferase, N-terminal Glutathione transferase family Intracellular chloride channel Thioredoxin-like superfamily
UniProtKB:A2CEF5 243
UniProtKB:Q6NXB5 408
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations