Gene
rps2
- ID
- ZDB-GENE-040426-2454
- Name
- ribosomal protein S2
- Symbol
- rps2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in epidermis; mesenchyme; nervous system; pectoral fin; and pharyngeal arch 3-7 skeleton. Orthologous to human RPS2 (ribosomal protein S2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85824 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la015097Tg | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018192 | Small ribosomal subunit protein uS5, N-terminal, conserved site |
| Domain | IPR005324 | Small ribosomal subunit protein uS5, C-terminal |
| Domain | IPR013810 | Small ribosomal subunit protein uS5, N-terminal |
| Family | IPR000851 | Small ribosomal subunit protein uS5 |
| Family | IPR005711 | Small ribosomal subunit protein uS5, eukaryotic/archaeal |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Ribosomal protein uS5 domain 2-type superfamily | Small ribosomal subunit protein uS5 | Small ribosomal subunit protein uS5, C-terminal | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Small ribosomal subunit protein uS5, eukaryotic/archaeal | Small ribosomal subunit protein uS5, N-terminal | Small ribosomal subunit protein uS5, N-terminal, conserved site |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NWC3 | InterPro PDB | 280 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-139G16 | ZFIN Curated Data | |
| Encodes | EST | fb10e01 | ||
| Encodes | EST | fc11d09 | Rauch et al., 2003 | |
| Encodes | EST | fc94f01 | ||
| Encodes | EST | fj09b04 | ||
| Encodes | EST | tdsubc_2h2 | ||
| Encodes | cDNA | MGC:85824 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213279 (1) | 1000 nt | ||
| Genomic | GenBank:CR392027 (1) | 110726 nt | ||
| Polypeptide | UniProtKB:Q6NWC3 (1) | 280 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | RPS2 | 16 | Amino acid sequence comparison (1) |
- Ugajin, N., Imami, K., Takada, H., Ishihama, Y., Chiba, S., Mishima, Y. (2023) Znf598-mediated Rps10/eS10 ubiquitination contributes to the ribosome ubiquitination dynamics during zebrafish development. RNA (New York, N.Y.). 29(12):1910-1927
- Wysocka, E., Gonicka, A., Anbalagan, S. (2023) CRISPR-Cas9 F0 knockout approach using predesigned in vitro transcribed guide RNAs partially recapitulates Rx3 function in eye morphogenesis. Journal of genetics. 102:
- Anbalagan, S., Gordon, L., Blechman, J., Matsuoka, R.L., Rajamannar, P., Wircer, E., Biran, J., Reuveny, A., Leshkowitz, D., Stainier, D.Y.R., Levkowitz, G. (2018) Pituicyte Cues Regulate the Development of Permeable Neuro-Vascular Interfaces. Developmental Cell. 47(6):711-726.e5
- Kwon, O.K., Kim, S.J., Lee, S. (2018) First profiling of lysine crotonylation of myofilament proteins and ribosomal proteins in zebrafish embryos. Scientific Reports. 8:3652
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wu, C.C., Tsai, T.H., Chang, C., Lee, T.T., Lin, C., Cheng, I.H., Sun, M.C., Chuang, Y.J., Chen, B.S. (2014) On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio. PLoS One. 9:e97902
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
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