Gene
ppib
- ID
- ZDB-GENE-040426-1955
- Name
- peptidylprolyl isomerase B (cyclophilin B)
- Symbol
- ppib Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to act upstream of or within protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including axis; hatching gland; notochord; pectoral fin musculature; and polster. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb87 (7 images)
- IMAGE:6909633 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| osteogenesis imperfecta type 9 | Alliance | Osteogenesis imperfecta, type IX | 259440 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclophilin-like domain superfamily | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain |
|---|---|---|---|---|
|
UniProtKB:Q6PBW4
|
216 |
Interactions and Pathways
No data available
Plasmids
No data available