Gene
fa2h
- ID
- ZDB-GENE-031219-4
- Name
- fatty acid 2-hydroxylase
- Symbol
- fa2h Nomenclature History
- Previous Names
-
- cb1044 (1)
- zgc:153777
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have fatty acid alpha-hydroxylase activity. Predicted to be involved in fatty acid metabolic process. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 35. Is expressed in EVL; digestive system; ectoderm; peripheral olfactory organ; and pronephric duct. Orthologous to human FA2H (fatty acid 2-hydroxylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1044 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 35 | Alliance | Spastic paraplegia 35, autosomal recessive | 612319 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b5 | Cytochrome b5, heme-binding site | Cytochrome b5-like heme/steroid binding domain | Cytochrome b5-like heme/steroid binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q0P3V8
|
102 |
Interactions and Pathways
No data available
Plasmids
No data available