Gene
aclya
- ID
- ZDB-GENE-031113-1
- Name
- ATP citrate lyase a
- Symbol
- aclya Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and fatty acid biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including axis; epidermis; nervous system; optic vesicle; and periderm. Orthologous to human ACLY (ATP citrate lyase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb722 (9 images)
- IMAGE:7162954 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Sun et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR017440 | ATP-citrate lyase/succinyl-CoA ligase, active site |
| Conserved_site | IPR017866 | Succinyl-CoA synthetase, beta subunit, conserved site |
| Conserved_site | IPR033847 | ATP-citrate lyase/succinyl-CoA ligase, conserved site |
| Domain | IPR003781 | CoA-binding |
| Domain | IPR005811 | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain |
| Domain | IPR032263 | ATP-citrate synthase, citrate-binding domain |
| Family | IPR002020 | Citrate synthase |
| Family | IPR014608 | ATP-citrate synthase |
| Homologous_superfamily | IPR016102 | Succinyl-CoA synthetase-like |
| Homologous_superfamily | IPR016142 | Citrate synthase-like, large alpha subdomain |
| Homologous_superfamily | IPR016143 | Citrate synthase-like, small alpha subdomain |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR036969 | Citrate synthase superfamily |
Domain Details Per Protein
| Protein | Length | ATP-citrate lyase/succinyl-CoA ligase, active site | ATP-citrate lyase/succinyl-CoA ligase, conserved site | ATP-citrate synthase | ATP-citrate synthase, citrate-binding domain | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | Citrate synthase | Citrate synthase-like, large alpha subdomain | Citrate synthase-like, small alpha subdomain | Citrate synthase superfamily | CoA-binding | NAD(P)-binding domain superfamily | Succinyl-CoA synthetase, beta subunit, conserved site | Succinyl-CoA synthetase-like |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DG67
|
1092 |
Interactions and Pathways
No data available
Plasmids
No data available