Gene
trpv1
- ID
- ZDB-GENE-030912-8
- Name
- transient receptor potential cation channel, subfamily V, member 1
- Symbol
- trpv1 Nomenclature History
- Previous Names
-
- TRPV1/2 (1)
- si:dkey-9e15.2
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have calcium channel activity. Involved in response to heat and thermosensory behavior. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in colorectal cancer; congenital stationary night blindness; focal nonepidermolytic palmoplantar keratoderma 2; migraine (multiple); and schizophrenia. Is expressed in several structures, including epithelium; heart; keratinocyte; nervous system; and pleuroperitoneal region. Orthologous to several human genes including TRPV1 (transient receptor potential cation channel subfamily V member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005821 | Ion transport domain |
Family | IPR008347 | Transient receptor potential cation channel subfamily V member 1-4 |
Family | IPR024862 | Transient receptor potential cation channel subfamily V |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ion transport domain | Transient receptor potential cation channel subfamily V | Transient receptor potential cation channel subfamily V member 1-4 |
---|---|---|---|---|---|---|
UniProtKB:B6RTA2
|
819 | |||||
UniProtKB:B0S711
|
813 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-trpv1 | polyclonal | IgG | Rabbit |
|
Thermo Fisher Scientific (Lab Vision)
|
2 |
Plasmids
No data available