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Gene

trpv1

ID
ZDB-GENE-030912-8
Name
transient receptor potential cation channel, subfamily V, member 1
Symbol
trpv1 Nomenclature History
Previous Names
  • TRPV1/2 (1)
  • si:dkey-9e15.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable calcium channel activity. Acts upstream of or within response to heat and thermosensory behavior. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including epithelium; heart; keratinocyte; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in colorectal cancer; congenital stationary night blindness; keratosis (multiple); migraine (multiple); and schizophrenia. Orthologous to several human genes including TRPV1 (transient receptor potential cation channel subfamily V member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chen et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpv1 Human Ortholog
No data available
Associated With trpv1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR020683 Ankyrin repeat-containing domain
Family IPR008347 Transient receptor potential channel, vanilloid 1-4
Family IPR024862 Transient receptor potential cation channel subfamily V
Family IPR024865 Transient receptor potential channel, vanilloid 2
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily Ion transport domain Transient receptor potential cation channel subfamily V Transient receptor potential channel, vanilloid 1-4 Transient receptor potential channel, vanilloid 2
UniProtKB:B0S711 813
UniProtKB:A0A1J0M1I2 819
UniProtKB:B6RTA2 819
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-trpv1 polyclonal IgG Rabbit
  • IHC
  • WB
Thermo Fisher Scientific (Lab Vision)
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations