Gene
ical1
- ID
- ZDB-GENE-030910-4
- Name
- islet cell autoantigen 1-like
- Symbol
- ical1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable membrane curvature sensor activity. Predicted to be involved in membrane bending and regulation of secretion. Predicted to be located in cytoplasm and endomembrane system. Predicted to be active in secretory granule membrane. Is expressed in central nervous system; hatching gland; and polster. Orthologous to human ICA1L (islet cell autoantigen 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb781 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | Arfaptin homology (AH) domain | Islet cell autoantigen 1/Ica1-like | Islet cell autoantigen Ica1, C-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3BA90 | InterPro | 514 | ||||
| UniProtKB:F1QC36 | InterPro | 569 | ||||
| UniProtKB:A0A8M9PLX1 | InterPro | 497 | ||||
| UniProtKB:A0A8M3B0A0 | InterPro | 585 | ||||
| UniProtKB:A0A8M3AT71 | InterPro | 515 | ||||
| UniProtKB:A0A8M2BD37 | InterPro | 568 | ||||
| UniProtKB:Q803N6 | InterPro | 569 | ||||
| UniProtKB:A0A8M3AT72 | InterPro | 586 | ||||
| UniProtKB:A0AB32TSW4 | InterPro | 498 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be ica based on amino acid similarity to human ICA1. Subsequent analysis suggests it is the ortholog of human ICA1L and mouse Ica1l based on amino acid similarity and conserved synteny.