Gene
ccdc80
- ID
- ZDB-GENE-030616-56
- Name
- coiled-coil domain containing 80
- Symbol
- ccdc80 Nomenclature History
- Previous Names
-
- si:bz20i5.2
- ssg1 (1)
- zgc:113236
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Acts upstream of or within regulation of systemic arterial blood pressure and somitogenesis. Predicted to be located in extracellular region. Predicted to be active in basement membrane. Is expressed in several structures, including cardiovascular system; mesonephric duct; nervous system; pleuroperitoneal region; and solid lens vesicle. Used to study pulmonary hypertension. Orthologous to human CCDC80 (coiled-coil domain containing 80).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912708 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| pulmonary hypertension | y1Tg + CRISPR1-ccdc80 | standard conditions | Sasagawa et al., 2016 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR025232 | Domain of unknown function DUF4174 |
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF4174 |
|---|---|---|
|
UniProtKB:B7SDQ7
|
867 | |
|
UniProtKB:Q90X49
|
867 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccdc80-201
(1)
|
Ensembl | 2,604 nt |
Interactions and Pathways
No data available
Plasmids
No data available